Pre- versus post-column oxidation liquid chromatography fluorescence detection of paralytic shellfish toxins.
نویسندگان
چکیده
Both pre- and post-column oxidation liquid chromatography methods with fluorescence detection are available for detecting paralytic shellfish toxins. Each method has been evaluated in multiple laboratories and validated as a potential alternative to the mouse bioassay. This communication compares the advantages and limitations of both methods. For a given laboratory, the selection of either method may be based primarily on practicality and less on any deficiencies in scientific merit.
منابع مشابه
Determination of Gonyautoxin-4 in Echinoderms and Gastropod Matrices by Conversion to Neosaxitoxin Using 2-Mercaptoethanol and Post-Column Oxidation Liquid Chromatography with Fluorescence Detection
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عنوان ژورنال:
- Toxicon : official journal of the International Society on Toxinology
دوره 57 4 شماره
صفحات -
تاریخ انتشار 2011